Histological evaluation of a biorevitalisation treatment with PDO wires

Introduction:
The hypothesis of bio revitalisation with absorbable suture in Poly-Di-Oxanon (PDO) not anchored has undoubtedly been the most widespread procedure in recent years.  This study aims to assess whether what has been said can be demonstrated scientifically.

Materials and methods:
5 patients were treated  with  biostimulation  of  absorbable  PDO,  Basic  type,  from  5  different  manufacturers.  Skin  biopsies were  performed  pre-treatment,  at  6  months,  1  year  and  18  months  post-treatment.  The samples were evaluated by optical microscope.  The  process of  mechanotransduction  has  instead  been  evaluated  using  the  voltage  clamp technique.

Results:
Optical microscopy showed an unspecific increase in the number of collagen fibres without a significant increase in collagen type III; elastic fibres, however, showed transitional morphological changes.  The  greatest  effect  of  these  changes  occurred  especially  at  6  months  post-treatment;  at  18  months  it  regressed  completely  to  restoration  of  the  initial  state.  The voltage clamp showed that mechanotransduction occurred. Thread: Not necessarily a method that results in improved aesthetic results with a positive functional biological effect. The technical object studied is one example.

Conclusions:
The study demonstrated histologically that the use of bio-revitalising wires in PDO determines fibrosis and functional fabric.

Get the full paper here.

Register for AAAM Hands-On Korean Thread Lifting Master Course Now.
Go Back to More Articles